The 49ers are already seeking relief for players and fans ahead of Sunday’s game at Levi’s Stadium, where the kickoff ...

San Francisco 49ers general manager John Lynch spoke on Friday about the team's contingency plan in case Fred Warner is out ...

The Arizona Cardinals and San Francisco 49ers have released their final injury report of the Week 5 practice slate. Both ...

Preview the Week 5 matchup between the San Francisco 49ers and Arizona Cardinals with predictions, odds, over/under, spread, ...

Budda Baker will make his 100th career NFL start for the Arizona Cardinals on Sunday amid rumors he might be dealt before the ...

The Arizona Cardinals got a significant injury boost Friday, as head coach Jonathan Gannon announced that tight end Trey ...

The Arizona Cardinals (1-3) are 7.5-point underdogs in a road NFC West matchup against the San Francisco 49ers (2-2) on ...

A matchup with the offensively challenged New England Patriots was just what the San Francisco 49ers' defense needed to get ...

Check out these betting insights and trends before placing player prop wagers on Kyler Murray for Sunday’s game, which starts ...

San Francisco got back on track in Week 4. Brock Purdy is second in the NFL in passing yards and Jordan Mason is second in ...

Kyler Murray and the Arizona Cardinals (1-3) have not been consistent and are banged up on the offensive line, but they have ...

The San Francisco 49ers look for their first back-to-back wins of the season when they host the division rival Arizona ...